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Those who received the NAC saw an overall improvement compared to those who were given a placebo

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Further analyses of iron ion levels and the lipid peroxidation markers GSH and MDA revealed that Fe 2+ and MDA levels were significantly higher following PE treatment relative to levels in control cells, while GSH levels were significantly reduced, and PQQ treatment significantly reversed all three of these PE-induced changes (Figures 4BD)

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The process of S -glutathionylation may proceed spontaneously by thiol-disulphide exchange

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Luc JG, Antonoff MB

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