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Supporters cited a larger international literature than for several other peptides, while FDA staff said the material it could evaluate remained insufficient for the proposed uses
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Yes, fatigue is recognised as a common adverse reaction in tirzepatide clinical trials, particularly for weight management
Figure 3 In another study comparing the neuroprotective effects of two other novel GLP-1/GIP dual receptor agonists (DA-JC4, DA-CH5) with the GLP-1 single receptor agonist liraglutide and the first-generation GLP-1/GIP dual receptor agonist DA-JC1 in MPTP-induced PD mice, the results concluded that the new dual receptor agonists have clear neuroprotective effects (112)
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