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Another recently discovered mechanism by which proteins and particulates and possibly bacteria can penetrate the mucosa is via GAPs, in which large solutes such as 10 kDa dextran and proteins such as albumin traverse the mucosa where they are presented to subepithelial dendritic cells [19, 53, 62]

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Zhao Y, Wang XQ, Liu RQ, Jiang FW, Wang JX, Chen MS, et al

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COAs should show HPLC-MS testing confirming correct amino acid sequence and purity levels of 98 percent or higher

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