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This suggests that Ex-4 mediates its protective effects through a GLP-1-R-SIRT1-p53 signaling axis [41]
Now, the largest and longest study to date examining its ocular safety suggests clinicians may need to add one more item to the counseling conversation
doi: 10.1111/dom.12593 28 KanoskiSEHayesMRSkibickaKP
These agents preferentially lower fasting and postprandial hyperglycemia according to their pharmacokinetic (PK) characteristics, while also being associated with body weight loss [1,2,3,4,5,6]
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