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The search strategy was based on a combination of keywords and subject headings, including: breast cancer, breast cancer and oxidative stress, breast cancer prevalence, reactive oxygen species in breast cancer, cancer statistics, medicinal plants in breast cancer treatment, dietary antioxidants and breast cancer, and antioxidants in breast cancer treatment. After the initial search, duplicate records were removed and the remaining studies were subjected to a two-stage screening process
But in reality, even the best options struggle to raise intracellular glutathione above its usual homeostatic range in healthy people
Consistency is more important than intensity
Other potential challenges include anatomical barriers of the anterior eye that limit glutathione delivery to the lens and intracellular barriers within the lens that limit glutathione delivery to different lens regions
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