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Extensive research involving transgenic mouse models (APP, 5FAD, SAMP8), Drosophila melanogaster , and human clinical trials has demonstrated their potential in reducing A burden, improving cognitive function, and restoring neuronal health
However, preterm infants still have a high risk of developing complications and poor outcomes, and this risk is even higher for infants born below their gestational age
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Therefore, we speculated that CBS is nonfunctional under supraphysiological cystine concentrations and investigated its function in a customized culture media containing cystine at a physiological concentration of 50 M or less
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