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By activating GLP-1 receptors in the brain, semaglutide helps reduce appetite and promote a feeling of fullness, leading to weight loss
In the landmark SCALE Obesity and Prediabetes trial, published in the New England Journal of Medicine, 3,731 patients without type 2 diabetes were randomized to receive either liraglutide 3.0mg or placebo daily for 56 weeks
Data availability Essential data is contained within the article
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