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The GLP-1 RAs appear to modify atherosclerosis in the arteries, much like statin medications that treat cholesterol, and takes about a year or more to demonstrate measurable benefits on risk for cardiovascular events, whereas the SGLT2i medications seem to affect heart and kidney function more prominently and faster, with benefits evident very soon after starting the medication
However, the full B vitamin complex contains seven other vitamins that can benefit health above and beyond what B12 can do on its ownplus, some of the B vitamins work synergistically
This improved tolerability can lead to better adherence and, consequently, more effective long-term management of alcohol dependency