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[5] Patients should be aware of important safety considerations, including the risk of pancreatitis (report severe persistent abdominal pain), gallbladder disease, potential worsening of diabetic retinopathy particularly with rapid HbA1c reduction, and increased hypoglycaemia risk when used with insulin or sulfonylureas

Constipation is more common overall, occurring in 1525% of patients, while diarrhea affects a smaller percentage but can be more disruptive when it does occur

Botanical drugs are derived from medicinal plants through standardized processes that ensure quality and contain one or more active metabolites

Side effects and safety warnings Patients taking semaglutide report experiencing gastrointestinal-related side effects, including vomiting, nausea, diarrhea, constipation, headache, and fatigue