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Peer-reviewed work on bacterial endotoxin (lipopolysaccharide, LPS) in injectable products shows LPS can drive inflammatory liver injury through innate immune activation, including TNF-alpha mediated pathways in animal models

The full peer-reviewed data will be important, but it really does suggest that addressing obesity, alongside immune-targeted therapy, may improve outcomes

At the same time, the pills could greatly improve access to the medication by lowering coststhe injections can cost hundreds of dollars per month out of pocket

Its eligibility criteria exclude many individuals with obesity who do not have the specific comorbidities listed