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The interlinked rising epidemic of insufficient sleep and diabetes mellitus
Comparison with Mendelian randomization analyses of BMI and T2D genetic liability Genetic association data for BMI were obtained from a meta-analysis of GWAS conducted in 694,649 individuals 72 and for T2D from the DIAMANTE consortium (80,154 cases and 853,816 controls) 73
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That makes Tirzepatide particularly useful in research focused on: GLP-1 vs dual agonist comparisons body-weight and appetite outcomes glucose homeostasis and insulin dynamics the transition from single-pathway to multi-pathway incretin modulation Published clinical findings on Tirzepatide Tirzepatide has become one of the most closely followed metabolic peptides because published human studies have reported substantial effects on body weight, glycaemic control and broader cardiometabolic markers
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