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A typical approach might look like this: At month -3, you stop semaglutide and begin a basal insulin (for example, Lantus, Levemir, or Tresiba)
Autophagy dysfunction has been demonstrated in renal tubular cells in both diabetic kidneys and experimental models of DKD (98)
Tirzepatide is administered as a once-weekly subcutaneous injection, with dosing typically initiated at 2.5 mg and gradually titrated upward every 4 weeks as tolerated
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