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[16] Additionally, gliotoxin acts as an inhibitor of farnesyl transferase
fumigatus cell lysates (Figure S7) using human IgG [anti-GliT] resulted in a 51% reduction of gliotoxin reductase (NADPH oxidase) activity (Figure 5D), in complete accordance with data in Figure 5C, further confirming enzyme specificity
Over time, it has become apparent that altered urate transport, both in the gut and the kidneys, has a vital role in the pathogenesis of hyperuricaemia-associated diseases
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