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[PMCID:PMC10597691]
Autologous hematopoietic stem cell transplants have been performed in a few cystinosis patients based upon the premise that tunneling nanotubes transport lysosomes bidirectionally between the stem cells and the patients parenchymal cells [158]
In clinical practice, SGLT2 inhibitors are often initiated first due to their oral administration and broader reimbursement, with GLP-1 receptor agonists subsequently added to address persistent hyperglycemia, excess body weight, or residual albuminuria [84,85]
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