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Appropriate dose adjustments or replacement with a suitable alternative should be done under your doctors supervision.

Thalidomide and its derivatives, such as lenalidomide and pomalidomide (Figure 24), are now used in combination with other medications to treat these conditions, with strict controls in place to prevent use during pregnancy and minimize the risk of birth defects

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Mortaz E, Adcock IM, Ricciardolo FL, Varahram M, Jamaati H, Velayati AA, Folkerts G, Garssen J (2015) Anti-inflammatory effects of Lactobacillus rahmnosus and Bifidobacterium breve on cigarette smoke activated human macrophages