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Any questions regarding the appropriateness of tirzepatide in the context of autoimmune disease should be discussed with qualified healthcare providers familiar with the patient's complete medical history

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The lack of thioredoxin response in these cells is particularly concerning as this antioxidant system protects tissues from the damaging effects associated with enhanced hydrogen peroxide levels [77], thereby preventing harmful oxidative events from occurring, such as DNA damage, protein damage, lipid peroxidation, vascular remodeling, and endothelial dysfunction [73]