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A randomize, double-blind, placebo controlled trial where patients were administrated with 100mg CoQ10 daily (N=30) or placebo (N=30) for 12 weeks showed that treated patients have: Significantly lower fasting plasma glucose Significantly lower serum insulin concentration Significantly lower total cholesterol concentration Significantly lower LDL-cholesterol concentration So Overall, CoQ10 supplementation for 12 weeks among subjects with PCOS had beneficial effects on glucose metabolism, serum total- and LDL-cholesterol levels
*Correspondence: Shinya Toyokuni, Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan e-mail: [email protected] This article was submitted to Experimental Pharmacology and Drug Discovery, a section of the journal Frontiers in Pharmacology
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