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Additionally, TB001 significantly inhibited the expression of p-Smad2/3, but no significant effects were observed with GO6983 or PD98059 treatment ( Figure 8D )
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Carnitines role in brain health: Besides fertility, carnitine is implicated in brain plasticity and cognitive functions, with acetylcarnitine influencing gene expression through histone acetylation
Source: Arrone, et al New England J of Medicine May 11, 2025 Researchers randomized about 1,500 people with obesity and without diabetes to be treated with either tirzepatide or semaglutide, both at the highest tolerable recommended doses, and followed them for 72 weeks
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