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Carotenoids, particularly -carotenoids, have free radical scavenging characteristics, quenching highly reactive singlet molecular oxygen ( 1 O 2 ) and reducing oxidative damage to cells

Morris 2012, Fujimura 2012)

Subsequently, the qualified interaction modes with the minimum ligand conformer energy and protein docking score were used to construct optimal VHL-DeTYR-3-TYR ternary complex 43 through pairwise RMSD analysis 44 (Supplementary Fig