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Topiramate appears to mute that response
12 However, Ala mutations at any of these positions hardly affected activity
In the subgroup analysis, although no significant differences were observed among the subgroups based on different baseline weight, control groups, and indications, significant weight regain was observed in each subgroup compared with the control group, that is, the weight regain after treatment discontinuation was consistent in obese patients with different characteristics
The medication also helps promote more consistent feelings of fullness, making it easier to stick to healthier eating habits
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