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Obesity can lead to chronic, debilitating, and even life-threatening health issues such as diabetes, heart disease, and high blood pressure, so increased access to GLP-1 weight loss drugs could improve the long-term health, well-being, and outcome for millions of Americans
4b) and promoting GLP-1 and insulin secretion (Fig
Two decades of clinical use, multiple cardiovascular outcome trials, and a growing list of approved indications now sit behind these molecules
Furthermore, they could show that cells lacking both SLC25A39 as well as its paralogue SLC25A40 exhibit defects in the activity and stability of proteins containing ironsulfur clusters (ISCs)
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