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The condition typically develops gradually, and early signs may be subtle or attributed to other causes
Author contributions XM: Methodology, Formal Analysis, Software, Writingoriginal draft, Funding acquisition
doi: 10.1016/0024-3205(89)90293-2 39
2025 reviews in Frontiers in Pharmacology emphasize that dosing, purity, and delivery variability make cross-study comparisons difficult
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