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Beyond glycemic control and weight loss, GLP-1-based therapies exhibit broader biological effects, including improvements in lipid metabolism, anti-inflammatory activity, reductions in oxidative stress, and favorable effects on vascular function and atherosclerosis, which contribute to cardiovascular risk reduction [2,3,4]
In this context, there is an emphasis on the need for a deeper understanding of the functions of FOXO in the nervous system, which could lead to the development of targeted research approaches for these severe diseases
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