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While semaglutide does not directly affect thyroid function at therapeutic doses, the FDA label includes a boxed warning about thyroid C-cell tumors observed in rodent studies, though the relevance to humans remains uncertain
Compared with fasted mice, satiated mice exhibited a markedly smaller inhibitory response during consumption (Figure 4, GJ)
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This is the washout period for semaglutide to avoid overlapping side effects
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