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GLP-1 receptor agonists cross the blood-brain barrier and interact with brain regions involved in appetite, reward processing, and potentially arousal
The incorporation of a 104-week treatment period and 52-week extension, resulting in a total treatment period of 156 weeks in evoke/evoke+, allows for a comprehensive evaluation of the time to dementia progression in participants with baseline MCI, as well as long-term efficacy
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The mechanism behind these side effects relates directly to how these medications work
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