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Users at lower body fat levels have less adipose tissue available for lipolysis, and the marginal returns from fat-mobilizing agents diminish as body fat decreases

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Quality assessment of included studies The risk of bias in the eligible included studies was assessed using the Cochrane criteria.[] The quality of all studies was assessed by two different authors (NK and BA) for following items: sequence generation, allocation sequence concealment, blinding of participants and researchers, and outcomes reporting to evaluate possible sources of bias [Figure 1]

Additionally, we conducted further experiments to measure the fully deuterated exchange profiles of arr1 to estimate back-exchange